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pab1 serine/threonine protein phosphatase PP2A regulatory subunit B-55 Pab1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541519, updated on 18-Sep-2024

Summary

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Official Symbol
pab1
Official Full Name
serine/threonine protein phosphatase PP2A regulatory subunit B-55 Pab1
Primary source
PomBase:SPAC227.07c
Locus tag
SPOM_SPAC227.07C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ret1
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Genomic context

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See pab1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (507522..509893, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene autophagy C terminal domain family protein Neighboring gene prefoldin subunit 4 Neighboring gene ncRNA Neighboring gene Rab GTPase-binding protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cleavage and polyadenylation specificity factor complex subunit Yth1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Wee1 and Cdc25 are controlled by conserved PP2A-dependent mechanisms in fission yeast. Lucena R, et al. Cell Cycle, 2017 Mar 4. PMID 28103117, Free PMC Article
  2. Ethanol-hypersensitive and ethanol-dependent cdc- mutants in Schizosaccharomyces pombe. Jimenez J, et al. Mol Gen Genet, 1994 Oct 17. PMID 7845361
  3. The regulatory subunits of fission yeast protein phosphatase 2A (PP2A) affect cell morphogenesis, cell wall synthesis and cytokinesis. Kinoshita K, et al. Genes Cells, 1996 Jan. PMID 9078365
  4. Feedback regulation of SIN by Etd1 and Rho1 in fission yeast. Alcaide-Gavilán M, et al. Genetics, 2014 Feb. PMID 24336750, Free PMC Article
  5. The protein phosphatase 2A B'-regulatory subunit par1p is implicated in regulation of the S. pombe septation initiation network. Le Goff X, et al. FEBS Lett, 2001 Nov 9. PMID 11707284

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphatase activator activity EXP
Inferred from Experiment
more info
 PubMed 
contributes_to protein phosphatase regulator activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of G2/M transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of induction of conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic spindle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein phosphatase type 2A complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein phosphatase type 2A complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine protein phosphatase PP2A regulatory subunit B-55 Pab1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    507522..509893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018361.3 → NP_592961.1  serine/threonine protein phosphatase PP2A regulatory subunit B-55 Pab1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_592961.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q12702, Q9UTD2
    Conserved Domains (3) summary
    COG5170
    Location:4 → 463
    CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
    sd00039
    Location:32 → 75
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:30 → 326
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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