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mms19 TFIIH regulator Mms19 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541536, updated on 14-Nov-2024

Summary

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Official Symbol
mms19
Official Full Name
TFIIH regulator Mms19
Primary source
PomBase:SPAC1071.02
Locus tag
SPOM_SPAC1071.02
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See mms19 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (3858218..3861822)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cleavage and polyadenylation specificity factor complex subunit Pta1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Sil1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene signal peptidase subunit Spc2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Coordination of DNA replication and histone modification by the Rik1-Dos2 complex. Li F, et al. Nature, 2011 Jul 3. PMID 21725325, Free PMC Article
  2. Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing. Chalamcharla VR, et al. Proc Natl Acad Sci U S A, 2015 Dec 22. PMID 26631744, Free PMC Article
  3. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
  4. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
  5. Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries. Wang J, et al. Genes Dev, 2013 Sep 1. PMID 24013502, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity NAS
Non-traceable Author Statement
more info
  
Process Evidence Code Pubs
involved_in protein maturation by iron-sulfur cluster transfer IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
part_of cytosolic [4Fe-4S] assembly targeting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in pericentric heterochromatin EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
TFIIH regulator Mms19

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3858218..3861822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019773.3 → NP_594352.1  TFIIH regulator Mms19 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594352.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UTR1
    Conserved Domains (2) summary
    pfam12460
    Location:528 → 953
    MMS19_C; RNAPII transcription regulator C-terminal
    pfam14500
    Location:46 → 304
    MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
Nucleotide Protein
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