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spb1 rRNA methyltransferase Spb1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542112, updated on 18-Sep-2024

Summary

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Official Symbol
spb1
Official Full Name
rRNA methyltransferase Spb1
Primary source
PomBase:SPAC1687.11
Locus tag
SPOM_SPAC1687.11
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See spb1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (922281..925133)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ENTH/VHS domain protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein mcp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquinone biosynthesis protein Coq4 Neighboring gene COP9/signalosome complex protease subunit Csn5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition. St Amour CV, et al. Mol Cell Biol, 2012 Jul. PMID 22508988, Free PMC Article
  2. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Zhang K, et al. Science, 2011 Mar 25. PMID 21436456, Free PMC Article
  3. Chromatin localization of nucleophosmin organizes ribosome biogenesis. Ugolini I, et al. Mol Cell, 2022 Dec 1. PMID 36423630, Free PMC Article
  4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables rRNA (guanine) methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (guanosine-2'-O-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (uridine-2'-O-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in assembly of large subunit precursor of preribosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of preribosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
rRNA methyltransferase Spb1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    922281..925133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018525.3 → NP_593129.1  rRNA methyltransferase Spb1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593129.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42832
    Conserved Domains (3) summary
    COG0293
    Location:1 → 205
    RlmE; 23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ [Translation, ribosomal structure and biogenesis]
    pfam07780
    Location:588 → 798
    Spb1_C; Spb1 C-terminal domain
    pfam11861
    Location:235 → 385
    DUF3381; Domain of unknown function (DUF3381)
Nucleotide Protein
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