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csx1 RNA-binding protein Csx1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542151, updated on 18-Sep-2024

Summary

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Official Symbol
csx1
Official Full Name
RNA-binding protein Csx1
Primary source
PomBase:SPAC17A2.09c
Locus tag
SPOM_SPAC17A2.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See csx1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3570007..3572345, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene spliceosome complex disassembly protein Ntr2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The RNA binding protein Csx1 promotes sexual differentiation in Schizosaccharomyces pombe. Matia-Gonzalez AM, et al. PLoS One, 2012. PMID 22253882, Free PMC Article
  2. RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress. Rodríguez-Gabriel MA, et al. EMBO J, 2003 Dec 1. PMID 14633985, Free PMC Article
  3. RNA-binding protein Csx1 is phosphorylated by LAMMER kinase, Lkh1, in response to oxidative stress in Schizosaccharomyces pombe. Kang WH, et al. FEBS Lett, 2007 Jul 24. PMID 17612531
  4. Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress. Martín V, et al. Mol Biol Cell, 2006 Mar. PMID 16407405, Free PMC Article
  5. Cellular stress induces cytoplasmic RNA granules in fission yeast. Nilsson D, et al. RNA, 2011 Jan. PMID 21098141, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A novel mechanism of ste11+ mRNA positive regulation through the activity of Csx1, is presented.
    Title: The RNA binding protein Csx1 promotes sexual differentiation in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in 3'-UTR-mediated mRNA stabilization EXP
Inferred from Experiment
more info
 PubMed 
involved_in 3'-UTR-mediated mRNA stabilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
NOT involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of gene expression EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of mRNA stability involved in response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasmic stress granule EXP
Inferred from Experiment
more info
 PubMed 
is_active_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
NOT is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA-binding protein Csx1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3570007..3572345 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019666.2 → NP_594243.1  RNA-binding protein Csx1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594243.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13759, Q09331, Q09335
    Conserved Domains (5) summary
    TIGR01645
    Location:217 → 577
    half-pint; poly-U binding splicing factor, half-pint family
    COG0724
    Location:67 → 367
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12346
    Location:296 → 367
    RRM3_NGR1_NAM8_like; RNA recognition motif 3 in yeast negative growth regulatory protein NGR1 (RBP1), yeast protein NAM8 and similar proteins
    cd12611
    Location:86 → 168
    RRM1_NGR1_NAM8_like; RNA recognition motif 1 in yeast negative growth regulatory protein NGR1, yeast protein NAM8 and similar proteins
    cd12613
    Location:181 → 260
    RRM2_NGR1_NAM8_like; RNA recognition motif 2 in yeast negative growth regulatory protein NGR1, yeast protein NAM8 and similar proteins
Nucleotide Protein
Heading Accession and Version

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