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pnu1 endodeoxyribonuclease Pnu1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542291, updated on 18-Sep-2024

Summary

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Official Symbol
pnu1
Official Full Name
endodeoxyribonuclease Pnu1
Primary source
PomBase:SPAC17C9.08
Locus tag
SPOM_SPAC17C9.08
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
end1; nuc1
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Genomic context

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See pnu1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (4484695..4486032, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene zf-C2H2 type zinc finger protein/UBA domain protein Neighboring gene G-protein-coupled receptor Stm1 Neighboring gene ncRNA Neighboring gene TIM22 inner membrane protein import complex subunit Tim13 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dolichyl glucosyltransferase Alg8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The end1 gene of Schizosaccharomyces pombe coding for a DNase is identical with the pnu1 gene coding for an RNase. Sakem B, et al. Yeast, 2007 Jan. PMID 17192844
  2. Isolation and characterization of the Schizosaccharomyces pombe cDNA encoding the mitochondrial endonuclease(1). Ikeda S, et al. Biochim Biophys Acta, 2001 May 28. PMID 11406279
  3. Isolation of type I and II DNA topoisomerase mutants from fission yeast: single and double mutants show different phenotypes in cell growth and chromatin organization. Uemura T, et al. EMBO J, 1984 Aug. PMID 6090122, Free PMC Article
  4. Conserved strategies of RNA polymerase I hibernation and activation. Heiss FB, et al. Nat Commun, 2021 Feb 3. PMID 33536435, Free PMC Article
  5. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA endonuclease activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables DNA nuclease activity EXP
Inferred from Experiment
more info
 PubMed 
enables RNA endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA endonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA nuclease activity EXP
Inferred from Experiment
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables single-stranded DNA endodeoxyribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables single-stranded DNA endodeoxyribonuclease activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial DNA catabolic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in mitochondrial RNA catabolic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in transcription elongation by RNA polymerase I EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase I complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
endodeoxyribonuclease Pnu1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4484695..4486032 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020026.4 → NP_594598.2  endodeoxyribonuclease Pnu1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594598.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10480, Q9HFA0
    Conserved Domains (2) summary
    smart00477
    Location:78 → 289
    NUC; DNA/RNA non-specific endonuclease
    COG1864
    Location:5 → 309
    NUC1; DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]
Nucleotide Protein
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