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mot2 CCR4-Not complex subunit Mot2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542325, updated on 18-Sep-2024

Summary

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Official Symbol
mot2
Official Full Name
CCR4-Not complex subunit Mot2
Primary source
PomBase:SPAC16C9.04c
Locus tag
SPOM_SPAC16C9.04C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
not4
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Genomic context

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See mot2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (796876..798802, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene export adaptor Nmd3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Clr6 histone deacetylase-associated PHD protein-1 Cph1 Neighboring gene ATP-dependent RNA helicase Upf1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading. Challal D, et al. Genetics, 2023 Aug 9. PMID 37279920, Free PMC Article
  2. The architecture of the Schizosaccharomyces pombe CCR4-NOT complex. Ukleja M, et al. Nat Commun, 2016 Jan 25. PMID 26804377, Free PMC Article
  3. RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not. Webster MW, et al. Elife, 2019 Jan 2. PMID 30601114, Free PMC Article
  4. mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases. Webster MW, et al. Mol Cell, 2018 Jun 21. PMID 29932902, Free PMC Article
  5. Ubiquitination-dependent control of sexual differentiation in fission yeast. Simonetti F, et al. Elife, 2017 Aug 25. PMID 28841135, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding ISM
Inferred from Sequence Model
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity EXP
Inferred from Experiment
more info
 PubMed 
enables ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear-transcribed mRNA poly(A) tail shortening IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulatory ncRNA-mediated gene silencing EXP
Inferred from Experiment
more info
 PubMed 
Component Evidence Code Pubs
part_of CCR4-NOT complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of CCR4-NOT complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of CCR4-NOT core complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 

General protein information

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Preferred Names
CCR4-Not complex subunit Mot2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    796876..798802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018475.3 → NP_593078.1  CCR4-Not complex subunit Mot2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593078.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09818
    Conserved Domains (3) summary
    COG5175
    Location:1 → 489
    MOT2; Transcriptional repressor [Transcription]
    cd12438
    Location:111 → 210
    RRM_CNOT4; RNA recognition motif in Eukaryotic CCR4-NOT transcription complex subunit 4 (NOT4) and similar proteins
    pfam14570
    Location:18 → 64
    zf-RING_4; RING/Ubox like zinc-binding domain
Nucleotide Protein
Heading Accession and Version

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