U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cul1 cullin 1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542393, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
cul1
Official Full Name
cullin 1
Primary source
PomBase:SPAC17G6.12
Locus tag
SPOM_SPAC17G6.12
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
pcu1
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cul1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (3612057..3614883)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene glucosidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein slt1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Trade-off and flexibility in the dynamic regulation of the cullin-RING ubiquitin ligase repertoire. Straube R, et al. PLoS Comput Biol, 2017 Nov. PMID 29149173, Free PMC Article
  2. Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase. Kominami K, et al. Genes Cells, 1998 Nov. PMID 9990507
  3. Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast. Osaka F, et al. EMBO J, 2000 Jul 3. PMID 10880460, Free PMC Article
  4. Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast. Bamps S, et al. Biochem Biophys Res Commun, 2004 Dec 24. PMID 15555586
  5. SCF(Pof1)-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast. Harrison C, et al. EMBO J, 2005 Feb 9. PMID 15660136, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables inositol hexakisphosphate binding EXP
Inferred from Experiment
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-macromolecule adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SCF ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
part_of nuclear SCF ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
cullin 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3612057..3614883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019682.3 → NP_594259.1  cullin 1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594259.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13790, Q9USB3, Q9UUL3
    Conserved Domains (3) summary
    smart00182
    Location:450 → 589
    CULLIN; Cullin
    smart00884
    Location:696 → 763
    Cullin_Nedd8; Cullin protein neddylation domain
    COG5647
    Location:1 → 767
    COG5647; Cullin, a subunit of E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.