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swc4 Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542412, updated on 18-Sep-2024

Summary

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Official Symbol
swc4
Official Full Name
Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4
Primary source
PomBase:SPAC9G1.13c
Locus tag
SPOM_SPAC9G1.13C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See swc4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (1995130..1996716, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene PAK-like GC kinase Sid1 Neighboring gene inositol polyphosphate phosphatase Neighboring gene ncRNA Neighboring gene mitotic septin Spn4 Neighboring gene tRNA (m1A) methyltransferase complex catalytic subunit Trm61 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dynamin family protein Vps1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Activity of a C-terminal plant homeodomain (PHD) of Msc1 is essential for function. Qiu X, et al. J Biol Chem, 2010 Nov 19. PMID 20858896, Free PMC Article
  2. Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast. Hou H, et al. J Biol Chem, 2010 Jan 15. PMID 19910462, Free PMC Article
  3. An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe. Kim HS, et al. Nat Struct Mol Biol, 2009 Dec. PMID 19915592, Free PMC Article
  4. Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast. Elías-Villalobos A, et al. Nat Commun, 2019 Nov 20. PMID 31748520, Free PMC Article
  5. Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs. Zofall M, et al. Nature, 2009 Sep 17. PMID 19693008, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription initiation-coupled chromatin remodeling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NuA4 histone acetyltransferase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Swr1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1995130..1996716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019001.4 → NP_593568.2  Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593568.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14308
    Conserved Domains (1) summary
    pfam16282
    Location:101 → 179
    SANT_DAMP1_like; SANT/Myb-like domain of DAMP1
Nucleotide Protein
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