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cwf2 zf-CCCH type zinc finger protein, Prp19 complex subunit, RNA-binding Cwf2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542531, updated on 18-Sep-2024

Summary

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Official Symbol
cwf2
Official Full Name
zf-CCCH type zinc finger protein, Prp19 complex subunit, RNA-binding Cwf2
Primary source
PomBase:SPAC3A12.11c
Locus tag
SPOM_SPAC3A12.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
cwc2; prp3
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Genomic context

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See cwf2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (1439245..1440558, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene urease accessory protein UreD Neighboring gene ncRNA Neighboring gene 60S ribosomal protein eL20 Neighboring gene ncRNA Neighboring gene F1-ATPase chaperone Atp11 Neighboring gene translation initiation factor eIF3j (p35) Neighboring gene calmodulin Cam1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. McDonald WH, et al. Mol Cell Biol, 1999 Aug. PMID 10409726, Free PMC Article
  2. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. Ohi MD, et al. RNA, 2002 Jun. PMID 12088152, Free PMC Article
  3. Structure of a yeast spliceosome at 3.6-angstrom resolution. Yan C, et al. Science, 2015 Sep 11. PMID 26292707
  4. Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe. Cipakova I, et al. Cell Cycle, 2019 Jul. PMID 31219728, Free PMC Article
  5. A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast. Bayne EH, et al. Genome Biol, 2014. PMID 25274039, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables U6 snRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pre-mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spliceosomal snRNP assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of Prp19 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Prp19 complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U2-type catalytic step 1 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2-type catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of post-mRNA release spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
zf-CCCH type zinc finger protein, Prp19 complex subunit, RNA-binding Cwf2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1439245..1440558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018769.3 → NP_593337.1  zf-CCCH type zinc finger protein, Prp19 complex subunit, RNA-binding Cwf2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593337.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P87126, Q9P8I7
    Conserved Domains (3) summary
    COG0724
    Location:171 → 346
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12360
    Location:173 → 247
    RRM_cwf2; RNA recognition motif in yeast pre-mRNA-splicing factor Cwc2 and similar proteins
    pfam16131
    Location:49 → 153
    Torus; Torus domain
Nucleotide Protein
Heading Accession and Version

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