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gar2 nucleolin [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542869, updated on 18-Sep-2024

Summary

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Official Symbol
gar2
Official Full Name
nucleolin
Primary source
PomBase:SPAC140.02
Locus tag
SPOM_SPAC140.02
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See gar2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1897462..1899491)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene succinate dehydrogenase iron-sulfur subunit protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene argonaute inhibitor protein 1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcription-facilitating histone chaperons interact with genomic and synthetic G4 structures. Pavlova II, et al. Int J Biol Macromol, 2020 Oct 1. PMID 32454109
  2. Ultrastructural changes in the Schizosaccharomyces pombe nucleolus following the disruption of the gar2+ gene, which encodes a nucleolar protein structurally related to nucleolin. Léger-Silvestre I, et al. Chromosoma, 1997 Jun. PMID 9211982
  3. The role of the Schizosaccharomyces pombe gar2 protein in nucleolar structure and function depends on the concerted action of its highly charged N terminus and its RNA-binding domains. Sicard H, et al. Mol Biol Cell, 1998 Aug. PMID 9693363, Free PMC Article
  4. gar2 is a nucleolar protein from Schizosaccharomyces pombe required for 18S rRNA and 40S ribosomal subunit accumulation. Gulli MP, et al. Nucleic Acids Res, 1995 Jun 11. PMID 7596817, Free PMC Article
  5. Ccp1 modulates epigenetic stability at centromeres and affects heterochromatin distribution in Schizosaccharomyces pombe. Lu M, et al. J Biol Chem, 2018 Aug 3. PMID 29899117, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding TAS
Traceable Author Statement
more info
 PubMed 
enables histone chaperone activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling TAS
Traceable Author Statement
more info
 PubMed 
involved_in rRNA metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in dense fibrillar component IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleolus HDA PubMed 
is_active_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nucleolin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1897462..1899491
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018965.3 → NP_593531.1  nucleolin [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593531.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O13707, P41891
    Conserved Domains (2) summary
    cd12447
    Location:264 → 339
    RRM1_gar2; RNA recognition motif 1 in yeast protein gar2 and similar proteins
    cd12448
    Location:368 → 439
    RRM2_gar2; RNA recognition motif 2 in yeast protein gar2 and similar proteins
Nucleotide Protein
Heading Accession and Version

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