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tps2 trehalose-phosphate synthase Tps2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543109, updated on 18-Sep-2024

Summary

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Official Symbol
tps2
Official Full Name
trehalose-phosphate synthase Tps2
Primary source
PomBase:SPAC3G6.09c
Locus tag
SPOM_SPAC3G6.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See tps2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5394489..5397348, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene sulfhydryl oxidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GARP complex subunit Vps51

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
  2. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
  3. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
  4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
  5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables trehalose-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in trehalose biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in trehalose metabolism in response to stress IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
trehalose-phosphate synthase Tps2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5394489..5397348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020406.3 → NP_594975.1  trehalose-phosphate synthase Tps2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594975.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14145
    Conserved Domains (4) summary
    cd03788
    Location:16 → 546
    GT1_TPS; Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a ...
    COG1877
    Location:558 → 835
    OtsB; Trehalose-6-phosphatase [Carbohydrate transport and metabolism]
    pfam00982
    Location:78 → 547
    Glyco_transf_20; Glycosyltransferase family 20
    pfam02358
    Location:579 → 812
    Trehalose_PPase; Trehalose-phosphatase
Nucleotide Protein
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