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ppr4 translation regulator Ppr4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543312, updated on 14-Nov-2024

Summary

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Official Symbol
ppr4
Official Full Name
translation regulator Ppr4
Primary source
PomBase:SPAC8C9.06c
Locus tag
SPOM_SPAC8C9.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ppr4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3649467..3654006, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene D-Tyr-tRNA deacylase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene rRNA processing protein Fyv7 Neighboring gene 40S ribosomal protein uS7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of ppr3, ppr4, ppr6 or ppr10 induces flocculation and filamentous growth in Schizosaccharomyces pombe. Su Y, et al. FEMS Microbiol Lett, 2018 Aug 1. PMID 29878109
  2. Loss of ppr3, ppr4, ppr6, or ppr10 perturbs iron homeostasis and leads to apoptotic cell death in Schizosaccharomyces pombe. Su Y, et al. FEBS J, 2017 Jan. PMID 27886462
  3. Sls1 and Mtf2 mediate the assembly of the Mrh5C complex required for activation of cox1 mRNA translation. Wang Y, et al. J Biol Chem, 2024 Apr. PMID 38499152, Free PMC Article
  4. A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression. Kühl I, et al. Nucleic Acids Res, 2011 Oct. PMID 21727087, Free PMC Article
  5. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Absence of ppr3, ppr4, ppr6 or ppr10 can result in nonsexual flocculation and filamentous growth of cells.
    Title: Disruption of ppr3, ppr4, ppr6 or ppr10 induces flocculation and filamentous growth in Schizosaccharomyces pombe.
  2. The results suggest that disrupted iron homeostasis in Deltappr3, Deltappr4, Deltappr6, and Deltappr10 mutants may lead to an increase in the level of ROS and induction of apoptotic cell death in S. pombe.
    Title: Loss of ppr3, ppr4, ppr6, or ppr10 perturbs iron homeostasis and leads to apoptotic cell death in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables mRNA 5'-UTR binding TAS
Traceable Author Statement
more info
 PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to mitochondrial ribosome binding EXP
Inferred from Experiment
more info
 PubMed 
enables translation activator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in mitochondrial gene expression IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial translation EXP
Inferred from Experiment
more info
 PubMed 
involved_in positive regulation of mitochondrial translational initiation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm HDA PubMed 
is_active_in extrinsic component of matrix side of mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
translation regulator Ppr4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3649467..3654006 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019700.3 → NP_594277.1  translation regulator Ppr4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594277.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14275
    Conserved Domains (1) summary
    sd00004
    Location:430 → 457
    PPR; PPR repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials