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pdc201 pyruvate decarboxylase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543400, updated on 18-Sep-2024

Summary

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Official Symbol
pdc201
Official Full Name
pyruvate decarboxylase
Primary source
PomBase:SPAC3G9.11c
Locus tag
SPOM_SPAC3G9.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See pdc201 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (3159811..3162245)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ala Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene holo-[acyl-carrier-protein] synthase new8 Neighboring gene exosome 3'-5' phosphorolytic exoribonuclease Rrp41

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A metabolic strategy to enhance long-term survival by Phx1 through stationary phase-specific pyruvate decarboxylases in fission yeast. Kim JY, et al. Aging (Albany NY), 2014 Jul. PMID 25102102, Free PMC Article
  2. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article
  3. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
  4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pyruvate decarboxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in aromatic amino acid family catabolic process to alcohol via Ehrlich pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in generation of precursor metabolites and energy NAS
Non-traceable Author Statement
more info
  
involved_in pyruvate metabolic process NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pyruvate decarboxylase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3159811..3162245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019502.3 → NP_594083.1  pyruvate decarboxylase [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594083.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42873
    Conserved Domains (4) summary
    cd07038
    Location:10 → 173
    TPP_PYR_PDC_IPDC_like; Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins
    COG3961
    Location:3 → 569
    PDC1; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]
    cd02005
    Location:370 → 557
    TPP_PDC_IPDC; Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of ...
    pfam00205
    Location:205 → 320
    TPP_enzyme_M; Thiamine pyrophosphate enzyme, central domain
Nucleotide Protein
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