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srb8 mediator complex subunit Med12 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543467, updated on 3-Dec-2024

Summary

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Official Symbol
srb8
Official Full Name
mediator complex subunit Med12
Primary source
PomBase:SPAC688.08
Locus tag
SPOM_SPAC688.08
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
med12
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Genomic context

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See srb8 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (3123163..3126653)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Rng10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial pyrimidine nucleotide transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mediator can regulate mitotic entry and direct periodic transcription in fission yeast. Banyai G, et al. Mol Cell Biol, 2014 Nov. PMID 25154415, Free PMC Article
  2. A chromatin-remodeling protein is a component of fission yeast mediator. Khorosjutina O, et al. J Biol Chem, 2010 Sep 24. PMID 20622008, Free PMC Article
  3. Cyclin C influences the timing of mitosis in fission yeast. Banyai G, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515143, Free PMC Article
  4. TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution. Samuelsen CO, et al. Proc Natl Acad Sci U S A, 2003 May 27. PMID 12738880, Free PMC Article
  5. Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways. Linder T, et al. Nucleic Acids Res, 2008 May. PMID 18310102, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in negative regulation of cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of mediator complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
mediator complex subunit Med12

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3123163..3126653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001430996.1 → NP_001417945.1  LOW QUALITY PROTEIN: mediator complex subunit Med12 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P6L8
    UniProtKB/TrEMBL
    A0AAN2L314
Nucleotide Protein
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