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slx4 structure-specific endonuclease subunit Slx4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543478, updated on 18-Sep-2024

Summary

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Official Symbol
slx4
Official Full Name
structure-specific endonuclease subunit Slx4
Primary source
PomBase:SPAC688.06c
Locus tag
SPOM_SPAC688.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See slx4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (3116880..3119173, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene glycosylceramide biosynthesis protein Neighboring gene ncRNA Neighboring gene AMMECR1 family protein Neighboring gene MIS12/MIND complex Mis14/Nsl1 Neighboring gene ncRNA Neighboring gene glutathione S-transferase Gst3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Rng10

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure and SUMO binding of Slx1-Slx4 complex. Lian FM, et al. Sci Rep, 2016 Jan 20. PMID 26787556, Free PMC Article
  2. Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonuclease. Coulon S, et al. Mol Biol Cell, 2006 Apr. PMID 16467377, Free PMC Article
  3. Slx1-Slx4 are subunits of a structure-specific endonuclease that maintains ribosomal DNA in fission yeast. Coulon S, et al. Mol Biol Cell, 2004 Jan. PMID 14528010, Free PMC Article
  4. Sws1 is a conserved regulator of homologous recombination in eukaryotic cells. Martín V, et al. EMBO J, 2006 Jun 7. PMID 16710300, Free PMC Article
  5. Genetic controls of DNA damage avoidance in response to acetaldehyde in fission yeast. Noguchi C, et al. Cell Cycle, 2017 Jan 2. PMID 27687866, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via break-induced replication ISO
Inferred from Sequence Orthology
more info
  
involved_in maintenance of rDNA IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitotic DNA replication ISO
Inferred from Sequence Orthology
more info
  
involved_in replication fork processing TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of Slx1-Slx4 complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in rDNA protrusion IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
structure-specific endonuclease subunit Slx4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3116880..3119173 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019488.3 → NP_594064.1  structure-specific endonuclease subunit Slx4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594064.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P6M0
    Conserved Domains (1) summary
    pfam09494
    Location:357 → 412
    Slx4; Slx4 endonuclease
Nucleotide Protein
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