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ryh1 Rab family GTPase Ryh1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543529, updated on 18-Sep-2024

Summary

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Official Symbol
ryh1
Official Full Name
Rab family GTPase Ryh1
Primary source
PomBase:SPAC4C5.02c
Locus tag
SPOM_SPAC4C5.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
hos1; sat7
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Genomic context

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See ryh1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (1192702..1195145, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudouridine-5'-phosphatase Pud1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multispanning membrane protein, CTNS/PQ domain protein Neighboring gene ncRNA Neighboring gene tRNA-Ala

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ryh1 gene in the fission yeast Schizosaccharomyces pombe encoding a GTP-binding protein related to ras, rho and ypt: structure, expression and identification of its human homologue. Hengst L, et al. EMBO J, 1990 Jun. PMID 2112088, Free PMC Article
  2. Genetic and functional interaction between Ryh1 and Ypt3: two Rab GTPases that function in S. pombe secretory pathway. He Y, et al. Genes Cells, 2006 Mar. PMID 16483310
  3. Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase. Ma Y, et al. Mol Genet Genomics, 2010 Sep. PMID 20623139
  4. Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P2 signaling. Li C, et al. Genes Cells, 2014 Mar. PMID 24350606
  5. Multiple crosstalk between TOR and the cell integrity MAPK signaling pathway in fission yeast. Madrid M, et al. Sci Rep, 2016 Nov 23. PMID 27876895, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables GTP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase regulator activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of TORC2 signaling EXP
Inferred from Experiment
more info
 PubMed 
involved_in positive regulation of TORC2 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
Rab family GTPase Ryh1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1192702..1195145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018646.3 → NP_593249.1  Rab family GTPase Ryh1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593249.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P17608
    Conserved Domains (2) summary
    smart00175
    Location:12 → 170
    RAB; Rab subfamily of small GTPases
    cd01861
    Location:12 → 172
    Rab6; Rab GTPase family 6 (Rab6)
Nucleotide Protein
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Gene LinkOut

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