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Sbp spermine binding protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 25540, updated on 4-Jan-2025

Summary

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Official Symbol
Sbpprovided by RGD
Official Full Name
spermine binding proteinprovided by RGD
Primary source
RGD:3623
See related
EnsemblRapid:ENSRNOG00000058058 AllianceGenome:RGD:3623
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zg16b
Summary
Predicted to enable polyamine binding activity. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Sbp in Genome Data Viewer
Location:
10q12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13450613..13473016)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (12946036..12968439)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (13289502..13309338)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene serine protease 21 Neighboring gene common salivary protein 1 Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene uncharacterized LOC120095045 Neighboring gene zymogen granule protein 16B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Prostatic spermine-binding protein. Cloning and nucleotide sequence of cDNA, amino acid sequence, and androgenic control of mRNA level. Chang CS, et al. J Biol Chem, 1987 Feb 25. PMID 3818623
  2. Correction of the cDNA-derived protein sequence of prostatic spermine binding protein: pivotal role of tandem mass spectrometry in sequence analysis. Anderegg RJ, et al. Biochemistry, 1988 Jun 14. PMID 3166977
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables polyamine binding TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
prostatic spermine-binding protein
Names
zymogen granule protein 16B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001309360.1 → NP_001296289.1  prostatic spermine-binding protein isoform 2

    See identical proteins and their annotated locations for NP_001296289.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2K4C9, A6HCN9
    Conserved Domains (1) summary
    cd09611
    Location:110 → 205
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

  2. NM_001399302.1 → NP_001386231.1  prostatic spermine-binding protein isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2K176, A6HCP0
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

  3. NM_013024.4 → NP_037156.3  prostatic spermine-binding protein isoform 1 precursor

    See identical proteins and their annotated locations for NP_037156.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).
    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A0G2K176, A6HCP0
    Related
    ENSRNOP00000071728.1, ENSRNOT00000083075.3
    Conserved Domains (1) summary
    cd09611
    Location:22 → 150
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    13450613..13473016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P08723.1 GenPept UniProtKB/Swiss-Prot:P08723

Gene LinkOut

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