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Or4k42 olfactory receptor family 4 subfamily K member 42 [ Mus musculus (house mouse) ]

Gene ID: 257662, updated on 27-Nov-2024

Summary

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Official Symbol
Or4k42provided by MGI
Official Full Name
olfactory receptor family 4 subfamily K member 42provided by MGI
Primary source
MGI:MGI:3031124
See related
Ensembl:ENSMUSG00000095809 AllianceGenome:MGI:3031124
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR248-9; Olfr1290
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

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See Or4k42 in Genome Data Viewer
Location:
2 E3; 2 56.75 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (111319563..111324160, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (111489218..111493815, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily G member 7 Neighboring gene olfactory receptor family 4 subfamily F member 4B Neighboring gene olfactory receptor family 4 subfamily F member 4, pseudogene 1 Neighboring gene olfactory receptor family 4 subfamily K member 43, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes. Favor J, et al. Genetics, 2009 Aug. PMID 19474196, Free PMC Article
  2. The chromosomal distribution of mouse odorant receptor genes. Sullivan SL, et al. Proc Natl Acad Sci U S A, 1996 Jan 23. PMID 8570653, Free PMC Article
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
olfactory receptor 1290

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278787.1 → NP_001265716.1  olfactory receptor 1290

    See identical proteins and their annotated locations for NP_001265716.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Variants 1, 2, and 3, encode the same protein.
    Source sequence(s)
    AL731699
    Consensus CDS
    CCDS50659.1
    UniProtKB/TrEMBL
    Q7TQX8, Q8K4Z8
    Related
    ENSMUSP00000150388.2, ENSMUST00000217611.2
    Conserved Domains (1) summary
    cl21561
    Location:31 → 304
    7tm_4; Olfactory receptor

  2. NM_001278788.1 → NP_001265717.1  olfactory receptor 1290

    See identical proteins and their annotated locations for NP_001265717.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3, encode the same protein.
    Source sequence(s)
    AL731699
    Consensus CDS
    CCDS50659.1
    UniProtKB/TrEMBL
    Q7TQX8, Q8K4Z8
    Related
    ENSMUSP00000097211.2, ENSMUST00000099616.2
    Conserved Domains (1) summary
    cl21561
    Location:31 → 304
    7tm_4; Olfactory receptor

  3. NM_146262.3 → NP_666374.2  olfactory receptor 1290

    See identical proteins and their annotated locations for NP_666374.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3, encode the same protein.
    Source sequence(s)
    AL731699
    Consensus CDS
    CCDS50659.1
    UniProtKB/TrEMBL
    Q7TQX8, Q8K4Z8
    Conserved Domains (1) summary
    cl21561
    Location:31 → 304
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    111319563..111324160 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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