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Or4x15 olfactory receptor family 4 subfamily X member 15 [ Mus musculus (house mouse) ]

Gene ID: 257665, updated on 27-Nov-2024

Summary

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Official Symbol
Or4x15provided by MGI
Official Full Name
olfactory receptor family 4 subfamily X member 15provided by MGI
Primary source
MGI:MGI:3031340
See related
Ensembl:ENSMUSG00000075064 AllianceGenome:MGI:3031340
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MOR228-4; Olfr1506
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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Genomic context

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See Or4x15 in Genome Data Viewer
Location:
2 E1; 2 50.14 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (90047739..90054815, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (90217395..90224471, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase, receptor type, J pseudogene Neighboring gene predicted gene, 38718 Neighboring gene STARR-seq mESC enhancer starr_05080 Neighboring gene protein tyrosine phosphatase, receptor type, J pseudogene Neighboring gene STARR-seq mESC enhancer starr_05081 Neighboring gene olfactory receptor family 4 subfamily B member 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
  2. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  3. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
olfactory receptor 1506
Names
GA_x5J8B7W1PMD-3116-4045
GA_x6K02T2RJGU-1819-2748

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146265.2 → NP_666377.2  olfactory receptor 1506

    See identical proteins and their annotated locations for NP_666377.2

    Status: VALIDATED

    Source sequence(s)
    AL928949
    Consensus CDS
    CCDS16409.1
    UniProtKB/TrEMBL
    A2ATW2, D3Z4B7, Q7TQQ1, Q8K500
    Related
    ENSMUSP00000149370.2, ENSMUST00000213994.3
    Conserved Domains (2) summary
    pfam00001
    Location:39 → 285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29 → 302
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    90047739..90054815 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318306.1 → XP_017173795.1  olfactory receptor 1506 isoform X1

    UniProtKB/TrEMBL
    Q7TQY9
    Conserved Domains (1) summary
    cd15939
    Location:23 → 289
    7tmA_OR4A-like; olfactory receptor 4A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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