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Or8b1d olfactory receptor family 8 subfamily B member 1D [ Mus musculus (house mouse) ]

Gene ID: 258781, updated on 4-Jan-2025

Summary

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Official Symbol
Or8b1dprovided by MGI
Official Full Name
olfactory receptor family 8 subfamily B member 1Dprovided by MGI
Primary source
MGI:MGI:3030749
See related
Ensembl:ENSMUSG00000057444 AllianceGenome:MGI:3030749
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Olfr915; MOR167-4
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene appears to represent a strain-specific polymorphic pseudogene in mouse, where some strains, including the C57BL/6 reference genome strain, have a non-functional allele, while other strains have a protein-coding allele. [provided by RefSeq, Jan 2019]
Annotation information
Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
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Genomic context

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See Or8b1d in Genome Data Viewer
Location:
9 A5.1; 9 20.87 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (38557886..38558818, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (38646590..38647522, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 8 subfamily B member 49 Neighboring gene olfactory receptor family 8 subfamily B member 50 Neighboring gene STARR-seq mESC enhancer starr_23826 Neighboring gene STARR-seq mESC enhancer starr_23827 Neighboring gene STARR-seq mESC enhancer starr_23828 Neighboring gene olfactory receptor family 8 subfamily B member 51 Neighboring gene olfactory receptor family 8 subfamily B member 52

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  2. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  3. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
  4. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 

General protein information

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Preferred Names
olfactory receptor 915
Names
GA_x6K02T2PVTD-32349884-32348952
olfactory receptor MOR167-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146785.2 → NP_666996.2  olfactory receptor 915

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1, coding) represents the non-reference strain functional allele and encodes the full-length protein. It is not present in some mouse strains, including the C57BL/6 strain of the reference genome.
    Source sequence(s)
    AC069561, BC111098
    UniProtKB/TrEMBL
    Q8VG54
    Conserved Domains (2) summary
    pfam00001
    Location:41 → 290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31 → 308
    7tm_4; Olfactory receptor

RNA

  1. NR_160723.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1, non-coding) includes a premature stop codon and represents the non-functional allele, as in the C57BL/6 reference genome.
    Source sequence(s)
    AC069561
    Related
    ENSMUST00000215191.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    38557886..38558818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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