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josd-1 ubiquitinyl hydrolase 1 [ Caenorhabditis elegans ]

Gene ID: 259492, updated on 9-Dec-2024

Summary

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Official Symbol
josd-1
Official Full Name
ubiquitinyl hydrolase 1
Primary source
WormBase:WBGene00022190
Locus tag
CELE_Y71H2AR.3
See related
AllianceGenome:WB:WBGene00022190
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. Orthologous to several human genes including JOSD1 (Josephin domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See josd-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (2836639..2838453)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene N(6)-L-threonylcarbamoyladenine synthase Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Thioredoxin domain-containing protein 17 Neighboring gene Peptidase C1A papain C-terminal domain-containing protein Neighboring gene CUB domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquitinyl hydrolase 1
NP_871685.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2836639..2838453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_181956.6 → NP_871685.1  ubiquitinyl hydrolase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_871685.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IAA2
    Conserved Domains (1) summary
    pfam02099
    Location:12 → 140
    Josephin
Nucleotide Protein
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Gene LinkOut

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