lmtr-3 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: lmtr-3
Official Full Name: Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5
Primary source: WormBase:WBGene00007390
Locus tag: CELE_C06H2.6
See related: AllianceGenome:WB:WBGene00007390
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in cellular response to amino acid stimulus and positive regulation of TOR signaling. Predicted to be part of Ragulator complex. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See lmtr-3 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 3

Sequence:: Chromosome: V; NC_003283.11 (11124303..11125053)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C06H2.1 (e-PCR)
- UniSTS:315438

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in cellular response to amino acid stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of TOR signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of TOR signaling	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Ragulator complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5

NP_001294694.1

Confirmed by transcript evidence

NP_001367011.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

11124303..11125053

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001380756.3 → NP_001367011.1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q8WQG5

Conserved Domains (1) summary

pfam08923
Location:1 → 120

MAPKK1_Int; Mitogen-activated protein kinase kinase 1 interacting
NM_001307765.3 → NP_001294694.1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001294694.1

Status: REVIEWED

UniProtKB/TrEMBL

N1NTE7

Conserved Domains (1) summary

pfam08923
Location:1 → 19

MAPKK1_Int; Mitogen-activated protein kinase kinase 1 interacting