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Vom2r44 vomeronasal 2 receptor 44 [ Rattus norvegicus (Norway rat) ]

Gene ID: 266778, updated on 4-Jan-2025

Summary

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Official Symbol
Vom2r44provided by RGD
Official Full Name
vomeronasal 2 receptor 44provided by RGD
Primary source
RGD:708515
See related
EnsemblRapid:ENSRNOG00000078605 AllianceGenome:RGD:708515
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Casrl1
Summary
Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Located in dendrite. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 21.6), Brain (RPKM 15.0) and 9 other tissues See more
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Genomic context

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See Vom2r44 in Genome Data Viewer
Location:
2q31
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (150643126..150685691)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (148497150..148536036)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (154601995..154636154)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 33 member 1 Neighboring gene guanine monophosphate synthase Neighboring gene vomeronasal 2 receptor, 45 Neighboring gene vomeronasal 2 receptor, 46

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Co-expression of putative pheromone receptors in the sensory neurons of the vomeronasal organ. Martini S, et al. J Neurosci, 2001 Feb 1. PMID 11157070, Free PMC Article
  2. A new multigene family of putative pheromone receptors. Ryba NJ, et al. Neuron, 1997 Aug. PMID 9292726
  3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pheromone receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in dendrite IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal type-2 receptor 1
Names
calcium-sensing receptor like 1
tissue-type vomeronasal neurons putative pheromone receptor V2R2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001415021.1 → NP_001401950.1  vomeronasal type-2 receptor 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    150643126..150685691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017590655.3 → XP_017446144.1  vomeronasal type-2 receptor 1 isoform X2

    Conserved Domains (4) summary
    pfam00003
    Location:502 → 746
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:31 → 384
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:428 → 478
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:22 → 418
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

  2. XM_006232438.5 → XP_006232500.1  vomeronasal type-2 receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_006232500.1

    UniProtKB/TrEMBL
    A6JVP8, F1LQ12, G3V7C5
    Related
    ENSRNOP00000099000.1, ENSRNOT00000132683.1
    Conserved Domains (4) summary
    pfam00003
    Location:622 → 866
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:86 → 504
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:548 → 598
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:46 → 538
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001099498.1: Suppressed sequence

    Description
    NM_001099498.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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