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abf-2 Antibacterial factor-related peptide 2 [ Caenorhabditis elegans ]

Gene ID: 266826, updated on 9-Dec-2024

Summary

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Official Symbol
abf-2
Official Full Name
Antibacterial factor-related peptide 2
Primary source
WormBase:WBGene00000013
Locus tag
CELE_C50F2.10
See related
AllianceGenome:WB:WBGene00000013
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Is expressed in excretory cell; marginal cell; and pharyngeal neurons. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See abf-2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003279.8 (3885631..3885888, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like modifier-activating enzyme 5 Neighboring gene Protein SYS1 homolog Neighboring gene Pre-mRNA-splicing factor SYF1 Neighboring gene CCHC-type domain-containing protein Neighboring gene Antibacterial factor-related peptide 1 Neighboring gene DUF281 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Overexpression of an antimicrobial peptide derived from C. elegans using an aggregation-prone protein coexpression system. Tomisawa S, et al. AMB Express, 2013 Aug 15. PMID 23945047, Free PMC Article
  2. Identification of virulence properties in Salmonella Typhimurium DT104 using Caenorhabditis elegans. Sahu SN, et al. PLoS One, 2013. PMID 24124587, Free PMC Article
  3. abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans. Kato Y, et al. Biochem J, 2002 Jan 15. PMID 11772394, Free PMC Article
  4. Resistance to antimicrobial peptides contributes to persistence of Salmonella typhimurium in the C. elegans intestine. Alegado RA, et al. Cell Microbiol, 2008 Jun. PMID 18221392
  5. Assessment of nanopolystyrene toxicity under fungal infection condition in Caenorhabditis elegans. Li D, et al. Ecotoxicol Environ Saf, 2020 Jul 1. PMID 32302863

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to fungus IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to other organism IEA
Inferred from Electronic Annotation
more info
  
involved_in killing of cells of another organism IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Antibacterial factor-related peptide 2
NP_491252.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3885631..3885888 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058851.6 → NP_491252.1  Antibacterial factor-related peptide 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491252.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EC68, Q9NL69
    Conserved Domains (1) summary
    pfam16839
    Location:24 → 77
    Antimicrobial25; Nematode antimicrobial peptide
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EC68.1

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