eif-1 SUI1 domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: eif-1
Official Full Name: SUI1 domain-containing protein
Primary source: WormBase:WBGene00020868
Locus tag: CELE_T27F7.3
See related: AllianceGenome:WB:WBGene00020868
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity; ribosomal small subunit binding activity; and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. Is expressed in several structures, including intestine; nervous system; pharyngeal-intestinal valve; pharynx; and rectal gland cell. Orthologous to several human genes including EIF1B (eukaryotic translation initiation factor 1B). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See eif-1 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 5

Sequence:: Chromosome: II; NC_003280.10 (4990831..4993580, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

eIF1 functions in ensuring the fidelity of AUG start codon recognition in a multicellular organism
Title: The role of eIF1 in translation initiation codon selection in Caenorhabditis elegans.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T27F7.1 (e-PCR)
- UniSTS:321078

T27F7.3 (e-PCR)
- UniSTS:319689

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribosomal small subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of eukaryotic 43S preinitiation complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: SUI1 domain-containing protein

NP_001254096.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

4990831..4993580 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001267167.4 → NP_001254096.1 SUI1 domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001254096.1

Status: REVIEWED

UniProtKB/TrEMBL

Q967F1

Conserved Domains (1) summary

cd11566
Location:25 → 108

eIF1_SUI1; Eukaryotic initiation factor 1