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Dup99B Ductus ejaculatorius peptide 99B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768691, updated on 4-Jan-2025

Summary

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Official Symbol
Dup99Bprovided by FlyBase
Official Full Name
Ductus ejaculatorius peptide 99Bprovided by FlyBase
Primary source
FLYBASE:FBgn0250832
Locus tag
Dmel_CG33495
See related
AllianceGenome:FB:FBgn0250832
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-SAGE:Wang-013; CG33495; Dmel\CG33495; DUP; DUP99b; DUP99B
Summary
Enables G protein-coupled receptor binding activity. Involved in G protein-coupled receptor signaling pathway; egg-laying behavior; and negative regulation of female receptivity, post-mating. Located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Dup99B in Genome Data Viewer
Location:
99B8-99B8; 3-99 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29715068..29715377, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25540790..25541099, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45569 Neighboring gene Odorant-binding protein 99d Neighboring gene Odorant-binding protein 99b Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46108

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ductus ejaculatorius peptide 99B (DUP99B), a novel Drosophila melanogaster sex-peptide pheromone. Saudan P, et al. Eur J Biochem, 2002 Feb. PMID 11846801
  2. Binding sites of Drosophila melanogaster sex peptide pheromones. Ottiger M, et al. J Neurobiol, 2000 Jul. PMID 10880132
  3. Common functional elements of Drosophila melanogaster seminal peptides involved in reproduction of Drosophila melanogaster and Helicoverpa armigera females. Fan Y, et al. Insect Biochem Mol Biol, 2000 Aug-Sep. PMID 10876124
  4. The evolution of sex peptide: sexual conflict, cooperation, and coevolution. Hopkins BR, et al. Biol Rev Camb Philos Soc, 2022 Aug. PMID 35249265, Free PMC Article
  5. Sex-peptides bind to two molecularly different targets in Drosophila melanogaster females. Ding Z, et al. J Neurobiol, 2003 Jun. PMID 12717705

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables hormone activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in egg-laying behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of female receptivity TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of female receptivity, post-mating IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of egg-laying behavior TAS
Traceable Author Statement
more info
 PubMed 
involved_in regulation of female receptivity, post-mating IEA
Inferred from Electronic Annotation
more info
  
involved_in sexual reproduction HEP PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space HDA PubMed 

General protein information

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Preferred Names
ductus ejaculatorius peptide 99B
Names
CG33495-PA
CG33495-PB
Dup99B-PA
Dup99B-PB
anon-SAGE:Wang-013

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29715068..29715377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206582.2 → NP_996305.1  ductus ejaculatorius peptide 99B, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996305.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3DMS6, P81160
    UniProtKB/TrEMBL
    D1Z366
    Conserved Domains (1) summary
    pfam08138
    Location:30 → 52
    Sex_peptide; Sex peptide (SP) family

  2. NM_001260430.1 → NP_001247359.1  ductus ejaculatorius peptide 99B, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247359.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K801
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K801 A0A0B4K801
P81160.2 P81160

Gene LinkOut

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