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Fs - Follistatin

Enables activin binding activity. Involved in negative regulation of BMP signaling pathway; negative regulation of activin receptor signaling pathway; and positive regulation of activin receptor signaling pathway. Located in extracellular region. Is expressed in several structures, including brain; germline cell; gonad; imaginal disc; and photoreceptor. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Orthologous to several human genes including FST (follistatin). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa