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Remo Remoulade [ Drosophila melanogaster (fruit fly) ]

Gene ID: 2768909, updated on 9-Dec-2024

Summary

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Official Symbol
Remoprovided by FlyBase
Official Full Name
Remouladeprovided by FlyBase
Primary source
FLYBASE:FBgn0030466
Locus tag
Dmel_CG15744
See related
AllianceGenome:FB:FBgn0030466
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15744; CT35992; Dmel\CG15744; Q7KV24_DROME
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to several human genes including ADGRA2 (adhesion G protein-coupled receptor A2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Remo in Genome Data Viewer
Location:
11E9-11E9; 1-42 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13288051..13294433)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13182084..13188466)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Histone deacetylase 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45018 Neighboring gene uncharacterized protein Neighboring gene Inositol 1,4,5-triphosphate kinase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila adhesion GPCR Remoulade regulates axon growth, branching, and guidance by modulating Rac1 GTPase. Yang X, et al. J Genet Genomics, 2024 Apr. PMID 38049063
  2. The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila. Vieira Contreras F, et al. Cell Rep, 2024 Jan 23. PMID 38180839
  3. Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation. Scholz N, et al. Nature, 2023 Mar. PMID 36890234
  4. Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity. Ulian-Benitez S, et al. PLoS Genet, 2017 Aug. PMID 28846707, Free PMC Article
  5. Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae. Zhang Z, et al. Neurosci Bull, 2020 Sep. PMID 32761438, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
remoulade
Names
CG15744-PA
Remo-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13288051..13294433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132642.3 → NP_572870.2  remoulade [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572870.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KV24
    Conserved Domains (7) summary
    smart00082
    Location:166 → 216
    LRRCT; Leucine rich repeat C-terminal domain
    smart00410
    Location:229 → 344
    IG_like; Immunoglobulin like
    sd00031
    Location:109 → 133
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:107 → 147
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:107 → 168
    LRR_8; Leucine rich repeat
    cl02422
    Location:366 → 412
    HRM; Hormone receptor domain
    cl21561
    Location:768 → 975
    7tm_4; Olfactory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KV24 Q7KV24

Gene LinkOut

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