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CD3D CD3 delta subunit of T-cell receptor complex [ Bos taurus (domestic cattle) ]

Gene ID: 281053, updated on 29-Jan-2025

Summary

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Official Symbol
CD3Dprovided by VGNC
Official Full Name
CD3 delta subunit of T-cell receptor complexprovided by VGNC
Primary source
VGNC:VGNC:27028
See related
BGD:BT21167; Ensembl:ENSBTAG00000006452
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See CD3D in Genome Data Viewer
Location:
chromosome: 15
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (29019453..29023621, complement)

Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene myelin protein zero like 2 Neighboring gene CD3 epsilon subunit of T-cell receptor complex Neighboring gene CD3 gamma subunit of T-cell receptor complex Neighboring gene U6 spliceosomal RNA Neighboring gene ubiquitination factor E4A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Identification of a bovine surface antigen uniquely expressed on CD4-CD8- T cell receptor gamma/delta+ T lymphocytes. Clevers H, et al. Eur J Immunol, 1990 Apr. PMID 1971793
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC127796

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive thymic T cell selection IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of alpha-beta T cell receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
T-cell surface glycoprotein CD3 delta chain
Names
CD3d molecule, delta (CD3-TCR complex)
T-cell receptor T3 delta chain
antigen CD3D, delta polypeptide (TiT3 complex)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034033.2 → NP_001029205.1  T-cell surface glycoprotein CD3 delta chain precursor

    See identical proteins and their annotated locations for NP_001029205.1

    Status: PROVISIONAL

    Source sequence(s)
    BC102857
    UniProtKB/Swiss-Prot
    Q28072, Q3SZH3
    UniProtKB/TrEMBL
    A0AAA9TMX5
    Related
    ENSBTAP00070042402.1, ENSBTAT00070069643.1
    Conserved Domains (2) summary
    pfam02189
    Location:143 → 161
    ITAM; Immunoreceptor tyrosine-based activation motif
    cl11960
    Location:26 → 91
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    29019453..29023621 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28072.2 GenPept UniProtKB/Swiss-Prot:Q28072

Gene LinkOut

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