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ENSA endosulfine alpha [ Bos taurus (domestic cattle) ]

Gene ID: 281142, updated on 27-Dec-2024

Summary

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Official Symbol
ENSAprovided by VGNC
Official Full Name
endosulfine alphaprovided by VGNC
Primary source
VGNC:VGNC:50171
See related
BGD:BT25170; Ensembl:ENSBTAG00000007123
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See ENSA in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (20098776..20105592)

Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene golgi phosphoprotein 3 like Neighboring gene enhancer of rudimentary homolog Neighboring gene ubiquitin-ribosomal protein eS31 fusion protein-like Neighboring gene uncharacterized LOC112445951 Neighboring gene MCL1 apoptosis regulator, BCL2 family member

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Endosulfine, endogenous ligand for the sulphonylurea receptor: isolation from porcine brain and partial structural determination of the alpha form. Virsolvy-Vergine A, et al. Diabetologia, 1996 Feb. PMID 8635664
  2. Alpha endosulfine is a novel molecule, structurally related to a family of phosphoproteins. Peyrollier K, et al. Biochem Biophys Res Commun, 1996 Jun 25. PMID 8687439
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC137433

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-endosulfine
Names
ARPP-19e

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001314005.1 → NP_001300934.1  alpha-endosulfine isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon and its 3' terminal exon extends past a splice site that is used in variant 1. This results in an early stop codon and novel 3' UTR, compared to variant 1. It encodes isoform 2, which has a shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    EV629449, EV691157, EV751319, NKLS02000003
    UniProtKB/TrEMBL
    A0A140T869, A0AAA9TD15
    Related
    ENSBTAP00000009379.4, ENSBTAT00000009379.5
    Conserved Domains (1) summary
    pfam04667
    Location:33 → 86
    Endosulfine; cAMP-regulated phosphoprotein/endosulfine conserved region

  2. NM_174050.2 → NP_776475.2  alpha-endosulfine isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    EV629449, EV703202, NKLS02000003
    UniProtKB/TrEMBL
    A0AAA9TD15
    Conserved Domains (1) summary
    pfam04667
    Location:33 → 86
    Endosulfine; cAMP-regulated phosphoprotein/endosulfine conserved region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    20098776..20105592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059881532.1 → XP_059737515.1  alpha-endosulfine isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P68210.1 GenPept UniProtKB/Swiss-Prot:P68210

Gene LinkOut

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