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IBSP integrin binding sialoprotein [ Bos taurus (domestic cattle) ]

Gene ID: 281233, updated on 4-Oct-2024

Summary

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Official Symbol
IBSPprovided by VGNC
Official Full Name
integrin binding sialoproteinprovided by VGNC
Primary source
VGNC:VGNC:30021
See related
BGD:BT10826; Ensembl:ENSBTAG00000000470
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See IBSP in Genome Data Viewer
Location:
chromosome: 6
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (36879556..36893874, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112447053 Neighboring gene uncharacterized LOC132345488 Neighboring gene matrix extracellular phosphoglycoprotein Neighboring gene uncharacterized LOC112447150 Neighboring gene uncharacterized LOC132345489 Neighboring gene transfer RNA alanine (anticodon CGC)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide association study reveals that the IBSP locus affects ear size in cattle. Shen J, et al. Heredity (Edinb), 2023 Jun. PMID 37016135, Free PMC Article
  2. Cloning and sequence analysis of bovine bone sialoprotein cDNA: conservation of acidic domains, tyrosine sulfation consensus repeats, and RGD cell attachment domain. Chenu C, et al. J Bone Miner Res, 1994 Mar. PMID 7514841
  3. Complete topographical distribution of both the in vivo and in vitro phosphorylation sites of bone sialoprotein and their biological implications. Salih E, et al. J Biol Chem, 2004 May 7. PMID 15004024
  4. A potential role for tetranectin in mineralization during osteogenesis. Wewer UM, et al. J Cell Biol, 1994 Dec. PMID 7798325, Free PMC Article
  5. Phosphorylation of purified bovine bone sialoprotein and osteopontin by protein kinases. Salih E, et al. J Biol Chem, 1996 Jul 12. PMID 8663267

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genome-wide association study reveals that the IBSP locus affects ear size in cattle.
    Title: Genome-wide association study reveals that the IBSP locus affects ear size in cattle.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in bone mineralization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ossification IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin-binding sialoprotein; bone sialoprotein 2
Names
BSP II
bone sialoprotein II
cell-binding sialoprotein
integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174084.3 → NP_776509.1  integrin-binding sialoprotein precursor

    See identical proteins and their annotated locations for NP_776509.1

    Status: PROVISIONAL

    Source sequence(s)
    S73144
    UniProtKB/Swiss-Prot
    Q28862
    UniProtKB/TrEMBL
    A0AAA9T2J8
    Related
    ENSBTAP00000000595.2, ENSBTAT00000000595.3
    Conserved Domains (1) summary
    pfam05432
    Location:17 → 307
    BSP_II; Bone sialoprotein II (BSP-II)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    36879556..36893874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059887312.1 → XP_059743295.1  bone sialoprotein 2 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SHC6
    Related
    ENSBTAP00000083315.1, ENSBTAT00000091455.1

  2. XM_010806004.3 → XP_010804306.1  bone sialoprotein 2 isoform X1

    See identical proteins and their annotated locations for XP_010804306.1

    UniProtKB/Swiss-Prot
    Q28862
    UniProtKB/TrEMBL
    A0AAA9T2J8
    Conserved Domains (1) summary
    pfam05432
    Location:17 → 307
    BSP_II; Bone sialoprotein II (BSP-II)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28862.1 GenPept UniProtKB/Swiss-Prot:Q28862

Gene LinkOut

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