U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PARG poly(ADP-ribose) glycohydrolase [ Bos taurus (domestic cattle) ]

Gene ID: 281377, updated on 27-Dec-2024

Summary

Go to the top of the page Help
Gene symbol
PARG
Gene description
poly(ADP-ribose) glycohydrolase
See related
BGD:BT26615; Ensembl:ENSBTAG00000023018
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PARG in Genome Data Viewer
Location:
chromosome: 28
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (43900411..44015134, complement)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132344154 Neighboring gene chromosome 28 C10orf53 homolog Neighboring gene oxoglutarate dehydrogenase L Neighboring gene small nucleolar RNA SNORA74 Neighboring gene translocase of inner mitochondrial membrane 23 homolog (yeast) Neighboring gene uncharacterized LOC132344155 Neighboring gene nuclear receptor coactivator 4

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase. Lin W, et al. J Biol Chem, 1997 May 2. PMID 9115250
  2. Analysis of poly(ADP-ribose) glycohydrolase activity in nuclear extracts from mammalian cells. Bernardi R, et al. Biochim Biophys Acta, 1997 Mar 7. PMID 9074616
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables poly(ADP-ribose) glycohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ATP generation from poly-ADP-D-ribose IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-sugar metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
poly(ADP-ribose) glycohydrolase
NP_776563.1
XP_010819000.2
XP_010819001.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174138.3 → NP_776563.1  poly(ADP-ribose) glycohydrolase

    See identical proteins and their annotated locations for NP_776563.1

    Status: PROVISIONAL

    Source sequence(s)
    U78975
    UniProtKB/Swiss-Prot
    O02776
    UniProtKB/TrEMBL
    F1MG95
    Related
    ENSBTAP00000031225.4, ENSBTAT00000031269.4
    Conserved Domains (2) summary
    PHA03169
    Location:161 → 482
    PHA03169; hypothetical protein; Provisional
    pfam05028
    Location:582 → 910
    PARG_cat; Poly (ADP-ribose) glycohydrolase (PARG)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    43900411..44015134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010820699.4 → XP_010819001.2  poly(ADP-ribose) glycohydrolase isoform X1

    UniProtKB/TrEMBL
    F1MG95
    Conserved Domains (1) summary
    pfam05028
    Location:499 → 827
    PARG_cat; Poly (ADP-ribose) glycohydrolase (PARG)

  2. XM_010820698.4 → XP_010819000.2  poly(ADP-ribose) glycohydrolase isoform X1

    UniProtKB/TrEMBL
    F1MG95
    Conserved Domains (1) summary
    pfam05028
    Location:499 → 827
    PARG_cat; Poly (ADP-ribose) glycohydrolase (PARG)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O02776.1 GenPept UniProtKB/Swiss-Prot:O02776

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials