SCIN scinderin [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: SCINprovided by VGNC
Official Full Name: scinderinprovided by VGNC
Primary source: VGNC:VGNC:34339
See related: EnsemblRapid:ENSBTAG00070012305
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (20624490..20702627)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings demonstrate that adseverin regulates features indicative of redifferentiation in passaged articular chondrocytes through modulation of the actin cytoskeleton.
Title: Adseverin, an actin binding protein, regulates articular chondrocyte phenotype.

Submit: New GeneRIF Correction

General gene information

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Markers

BZ931126 (e-PCR)
- UniSTS:475158

SCIN (e-PCR)
- UniSTS:279063

SCIN (e-PCR)
- UniSTS:503605

MARC_39141-39142:1075480861:1 (e-PCR)
- UniSTS:467361

MARC_39143-39144:1075481186:1 (e-PCR)
- UniSTS:467362

MARC_39145-39146:1075481451:1 (e-PCR)
- UniSTS:467363

MARC_39147-39148:1075481699:1 (e-PCR)
- UniSTS:467364

MARC_39149-39150:1075483247:1 (e-PCR)
- UniSTS:467365

MARC_39153-39154:1075908815:1 (e-PCR)
- UniSTS:467367

MARC_39155-39156:1075494918:1 (e-PCR)
- UniSTS:467368

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin filament binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphatidylinositol-4,5-bisphosphate binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament severing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in actin polymerization or depolymerization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in barbed-end actin filament capping	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell projection assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in central nervous system development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in actin cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: scinderin

Names: SC; adseverin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.