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SDHD succinate dehydrogenase complex subunit D [ Bos taurus (domestic cattle) ]

Gene ID: 281481, updated on 1-Jan-2025

Summary

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Official Symbol
SDHDprovided by VGNC
Official Full Name
succinate dehydrogenase complex subunit Dprovided by VGNC
Primary source
VGNC:VGNC:110065
See related
Ensembl:ENSBTAG00000016266
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
CII4; QPs3; cybS; CII-4
Orthologs
human mouse all
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Genomic context

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See SDHD in Genome Data Viewer
Location:
chromosome: 15
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (22397456..22409059)

Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene PIH1 domain containing 2 Neighboring gene NKAP domain containing 1 Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene ATM interactor-like Neighboring gene interleukin 18

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. The smallest membrane anchoring subunit (QPs3) of bovine heart mitochondrial succinate-ubiquinone reductase. Cloning, sequencing, topology, and Q-binding domain. Shenoy SK, et al. J Biol Chem, 1997 Jul 11. PMID 9211943
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables succinate dehydrogenase (quinone) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquinone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial electron transport, succinate to ubiquinone IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
Names
malate dehydrogenase [quinone] cytochrome b small subunit
succinate dehydrogenase complex, subunit D, integral membrane protein
succinate-ubiquinone reductase membrane anchor subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174179.2 → NP_776604.1  succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor

    See identical proteins and their annotated locations for NP_776604.1

    Status: PROVISIONAL

    Source sequence(s)
    U50987
    UniProtKB/Swiss-Prot
    Q3T0U6, Q5UAB3, Q95123
    Related
    ENSBTAP00000021636.6, ENSBTAT00000021636.7
    Conserved Domains (1) summary
    cd03496
    Location:59 → 157
    SQR_TypeC_CybS; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Eukaryotic SQRs reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    22397456..22409059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024974988.2 → XP_024830756.1  succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0AAA9STC4, B8Y899
    Related
    ENSBTAP00000089674.1, ENSBTAT00000097527.1
    Conserved Domains (1) summary
    cd03496
    Location:85 → 183
    SQR_TypeC_CybS; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Eukaryotic SQRs reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric ...

  2. XM_024974989.2 → XP_024830757.1  succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0AAA9TR76
    Related
    ENSBTAP00000100870.1, ENSBTAT00000110541.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95123.2 GenPept UniProtKB/Swiss-Prot:Q95123

Gene LinkOut

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Molecular Biology Databases
Research Materials