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AMELX amelogenin, X-linked [ Bos taurus (domestic cattle) ]

Gene ID: 281620, updated on 1-Jan-2025

Summary

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Gene symbol
AMELX
Gene description
amelogenin, X-linked
See related
BGD:BT17359; Ensembl:ENSBTAG00000012089
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
AMLX; amelogenin
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See AMELX in Genome Data Viewer
Location:
chromosome: Un
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) Unplaced Scaffold NW_020192294.1 (129570..137470, complement)

NW_020192294.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 6 Neighboring gene holocytochrome c synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020192294 Unplaced Scaffold Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Identification of the chondrogenic-inducing activity from bovine dentin (bCIA) as a low-molecular-mass amelogenin polypeptide. Nebgen DR, et al. J Dent Res, 1999 Sep. PMID 10512382
  2. Analysis of amelogenin mRNA during bovine tooth development. Yuan ZA, et al. Arch Oral Biol, 1996 Feb. PMID 8712976
  3. Regulation of amelogenin gene expression during tooth development. Chen E, et al. Dev Dyn, 1994 Mar. PMID 8018986
  4. Complete amino acid sequence of amelogenin in developing bovine enamel. Takagi T, et al. Biochem Biophys Res Commun, 1984 Jun 15. PMID 6732825
  5. Heterogeneity of amelogenin mRNA in the bovine tooth germ. Shimokawa H, et al. J Biol Chem, 1987 Mar 25. PMID 3549722

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables structural constituent of tooth enamel IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in enamel mineralization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
amelogenin, X isoform
Names
X-chromosomal amelogenin
amelogenin (X chromosome)
amelogenin (amelogenesis imperfecta 1, X-linked)
class I amelogenin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014984.1 → NP_001014984.1  amelogenin, X isoform precursor

    Status: PROVISIONAL

    Source sequence(s)
    M63499
    UniProtKB/Swiss-Prot
    P02817
    UniProtKB/TrEMBL
    A0AAA9TFM7
    Related
    ENSBTAP00000016034.5, ENSBTAT00000016034.6
    Conserved Domains (1) summary
    smart00818
    Location:28 → 213
    Amelogenin; Amelogenins, cell adhesion proteins, play a role in the biomineralisation of teeth

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NW_020192294.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    129570..137470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059884539.1 → XP_059740522.1  amelogenin, X isoform isoform X1

    UniProtKB/TrEMBL
    A0AAA9TFM7
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02817.2 GenPept UniProtKB/Swiss-Prot:P02817

Gene LinkOut

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