CRYGB crystallin gamma B [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CRYGBprovided by VGNC
Official Full Name: crystallin gamma Bprovided by VGNC
Primary source: VGNC:VGNC:55341
See related: BGD:BT20570; Ensembl:ENSBTAG00000021770
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

Location:: chromosome: 2

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (96417868..96420083, complement)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Gamma-B crystallin synonymous codons provide a secondary code for protein folding in the cell.
Title: Synonymous Codons Direct Cotranslational Folding toward Different Protein Conformations.
The results are consistent with the hypothesis that short-range, weak, attractive interactions between alpha- and gamma-crystallins are necessary for maximum transparency of the lens.
Title: Age-dependent association of gamma-crystallins with aged alpha-crystallins from old bovine lens.
results suggest that two regions of gamma-B crystallin (residues 61-74, 145-159) play key roles in aggregative interactions. The regions, each containing a single-turn helix in the native structure, are located in structurally analogous positions
Title: Peptide scanning-based identification of regions of gamma-II crystallin involved in thermal aggregation: evidence of the involvement of structurally analogous, helix-containing loops from the two double Greek key domains of the molecule.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables structural constituent of eye lens	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in lens development in camera-type eye	IEA Inferred from Electronic Annotation more info	PubMed
involved_in visual perception	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: gamma-crystallin B

Names: gamma-B-crystallin; gamma-crystallin II; gammaB-crystallin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.