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GNGT1 G protein subunit gamma transducin 1 [ Bos taurus (domestic cattle) ]

Gene ID: 281796, updated on 27-Dec-2024

Summary

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Official Symbol
GNGT1provided by VGNC
Official Full Name
G protein subunit gamma transducin 1provided by VGNC
Primary source
VGNC:VGNC:29470
See related
BGD:BT28808; Ensembl:ENSBTAG00000002674
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See GNGT1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (11210171..11235219)

Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene G protein subunit gamma 11 Neighboring gene Bet1 golgi vesicular membrane trafficking protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Partial cDNA sequence of the gamma subunit of transducin. Van Dop C, et al. Biochem Biophys Res Commun, 1984 Oct 15. PMID 6149748
  2. Complete amino acid sequence of gamma-subunit of the GTP-binding protein from cattle retina. Ovchinnikov YuA, et al. FEBS Lett, 1985 Jan 1. PMID 3917402
  3. cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments. Yatsunami K, et al. Proc Natl Acad Sci U S A, 1985 Apr. PMID 2984674, Free PMC Article
  4. Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding. Fukada Y, et al. Nature, 1990 Aug 16. PMID 2385292
  5. The gamma subunit of transducin is farnesylated. Lai RK, et al. Proc Natl Acad Sci U S A, 1990 Oct. PMID 2217200, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The PIP2-induced orientation of the GRK2-Gbeta1gamma2 complex is therefore most likely caused by specific interactions between PIP2 and the GRK2 PH domain.
    Title: Effect of Lipid Composition on the Membrane Orientation of the G Protein-Coupled Receptor Kinase 2-Gβ1γ2 Complex.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G-protein beta-subunit binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein G(T) subunit gamma-T1
Names
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
transducin gamma chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174327.3 → NP_776752.1  guanine nucleotide-binding protein G(T) subunit gamma-T1

    See identical proteins and their annotated locations for NP_776752.1

    Status: VALIDATED

    Source sequence(s)
    K03255
    UniProtKB/Swiss-Prot
    P02698
    Related
    ENSBTAP00000003465.3, ENSBTAT00000003465.4
    Conserved Domains (1) summary
    smart00224
    Location:12 → 74
    GGL; G protein gamma subunit-like motifs

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    11210171..11235219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024990465.2 → XP_024846233.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

    Conserved Domains (1) summary
    smart00224
    Location:18 → 80
    GGL; G protein gamma subunit-like motifs

  2. XM_010803983.4 → XP_010802285.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X2

    See identical proteins and their annotated locations for XP_010802285.1

    UniProtKB/Swiss-Prot
    P02698
    Conserved Domains (1) summary
    smart00224
    Location:12 → 74
    GGL; G protein gamma subunit-like motifs
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02698.2 GenPept UniProtKB/Swiss-Prot:P02698

Gene LinkOut

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