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GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 [ Bos taurus (domestic cattle) ]

Gene ID: 282236, updated on 1-Jan-2025

Summary

Official Symbol
GABRA2provided by VGNC
Official Full Name
gamma-aminobutyric acid type A receptor subunit alpha2provided by VGNC
Primary source
VGNC:VGNC:107246
See related
BGD:BT10060; Ensembl:ENSBTAG00000011817
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See GABRA2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (64814826..64961988, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345586 Neighboring gene kinesin-like protein KIF3C Neighboring gene gamma-aminobutyric acid type A receptor subunit gamma1 Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene histone-lysine N-methyltransferase SETMAR-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Expression

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

General gene information

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
part_of GABA-A receptor complex PubMed 
located_in dendrite membrane PubMed 
located_in neuron projection PubMed 
located_in plasma membrane PubMed 
located_in postsynapse PubMed 
located_in synapse PubMed 

General protein information

Preferred Names
gamma-aminobutyric acid receptor subunit alpha-2
Names
GABA(A) receptor subunit alpha-2
GABAAR subunit alpha-2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
gamma-aminobutyric acid type A receptor alpha2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174541.2 → NP_776966.1  gamma-aminobutyric acid receptor subunit alpha-2 precursor

    See identical proteins and their annotated locations for NP_776966.1

    Status: PROVISIONAL

    Source sequence(s)
    X12361
    UniProtKB/Swiss-Prot
    P10063
    UniProtKB/TrEMBL
    A0AAA9SAQ2
    Related
    ENSBTAP00000015688.5, ENSBTAT00000015688.5
    Conserved Domains (3) summary
    TIGR00860
    Location:13 → 440
    LIC; Cation transporter family protein
    pfam02931
    Location:43 → 250
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:257 → 437
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    64814826..64961988 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024993020.2 → XP_024848788.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0AAA9S919, A0AAA9SAQ2
    Related
    ENSBTAP00000082564.1, ENSBTAT00000099064.1
    Conserved Domains (1) summary
    cl27321
    Location:13 → 500
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
  2. XM_024993019.2 → XP_024848787.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0AAA9SAQ2, F1MHX4
    Conserved Domains (2) summary
    TIGR00860
    Location:13 → 440
    LIC; Cation transporter family protein
    cd19035
    Location:47 → 249
    LGIC_ECD_GABAAR_A2; extracellular domain of gamma-aminobutyric acid receptor subunit alpha-2 (GABAAR-A2 or GABRA2)
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