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PAFAH2 platelet activating factor acetylhydrolase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 282299, updated on 27-Dec-2024

Summary

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Official Symbol
PAFAH2provided by VGNC
Official Full Name
platelet activating factor acetylhydrolase 2provided by VGNC
Primary source
VGNC:VGNC:32552
See related
BGD:BT25444; Ensembl:ENSBTAG00000005105
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PAFAH2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (127089906..127129392)

Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 30 member 2 Neighboring gene exostosin like glycosyltransferase 1 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene stathmin 1 Neighboring gene uncharacterized LOC132343451 Neighboring gene progestin and adipoQ receptor family member 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Protection against oxidative stress-induced cell death by intracellular platelet-activating factor-acetylhydrolase II. Matsuzawa A, et al. J Biol Chem, 1997 Dec 19. PMID 9405438
  2. Purification and characterization of platelet-activating factor acetylhydrolase II from bovine liver cytosol. Hattori K, et al. J Biol Chem, 1995 Sep 22. PMID 7673213
  3. cDNA cloning and expression of intracellular platelet-activating factor (PAF) acetylhydrolase II. Its homology with plasma PAF acetylhydrolase. Hattori K, et al. J Biol Chem, 1996 Dec 20. PMID 8955149
  4. Platelet-activating factor acetylhydrolases. Stafforini DM, et al. J Biol Chem, 1997 Jul 18. PMID 9218411
  5. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC127261

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-alkyl-2-acetylglycerophosphocholine esterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
platelet-activating factor acetylhydrolase 2, cytoplasmic
Names
PAF acetylhydrolase II
PAF:lysophospholipid transacetylase
PAF:sphingosine transacetylase
SD-PLA2
platelet-activating factor acetylhydrolase 2, 40kDa
platelet-activating factor acetyltransferase PAFAH2
serine-dependent phospholipase A2
NP_776995.1
XP_059747748.1
XP_059747749.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174570.2 → NP_776995.1  platelet-activating factor acetylhydrolase 2, cytoplasmic

    See identical proteins and their annotated locations for NP_776995.1

    Status: PROVISIONAL

    Source sequence(s)
    D87559
    UniProtKB/Swiss-Prot
    P79106, Q5E9S1
    UniProtKB/TrEMBL
    A0AAA9TE70
    Related
    ENSBTAP00000006727.5, ENSBTAT00000006727.7
    Conserved Domains (1) summary
    pfam03403
    Location:1 → 381
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    127089906..127129392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059891765.1 → XP_059747748.1  platelet-activating factor acetylhydrolase 2, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0AAA9TE70

  2. XM_059891766.1 → XP_059747749.1  platelet-activating factor acetylhydrolase 2, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0AAA9TE70
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P79106.1 GenPept UniProtKB/Swiss-Prot:P79106

Gene LinkOut

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