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PLA2G7 phospholipase A2 group VII [ Bos taurus (domestic cattle) ]

Gene ID: 282311, updated on 29-Jan-2025

Summary

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Official Symbol
PLA2G7provided by VGNC
Official Full Name
phospholipase A2 group VIIprovided by VGNC
Primary source
VGNC:VGNC:32965
See related
BGD:BT24959; Ensembl:ENSBTAG00000019315
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PLA2G7 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (19925027..19963288, complement)

Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 27 Neighboring gene tudor domain containing 6 Neighboring gene ankyrin repeat domain 66 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene meprin A subunit alpha

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Tjoelker LW, et al. Nature, 1995 Apr 6. PMID 7700381
  2. Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. Tjoelker LW, et al. J Biol Chem, 1995 Oct 27. PMID 7592717
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-alkyl-2-acetylglycerophosphocholine esterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
platelet-activating factor acetylhydrolase
Names
1-alkyl-2-acetylglycerophosphocholine esterase
2-acetyl-1-alkylglycerophosphocholine esterase
LDL-PLA(2)
LDL-associated phospholipase A2
PAF 2-acylhydrolase
PAF acetylhydrolase
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
NP_777003.2
XP_005223433.1
XP_005223434.1
XP_005223435.1
XP_005223436.1
XP_010816468.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174578.4 → NP_777003.2  platelet-activating factor acetylhydrolase precursor

    See identical proteins and their annotated locations for NP_777003.2

    Status: PROVISIONAL

    Source sequence(s)
    BC114827
    UniProtKB/Swiss-Prot
    Q28017
    UniProtKB/TrEMBL
    Q1RML9
    Related
    ENSBTAP00070042916.1, ENSBTAT00070070465.1
    Conserved Domains (1) summary
    pfam03403
    Location:52 → 417
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19925027..19963288 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005223376.4 → XP_005223433.1  platelet-activating factor acetylhydrolase isoform X1

    See identical proteins and their annotated locations for XP_005223433.1

    UniProtKB/Swiss-Prot
    Q28017
    UniProtKB/TrEMBL
    Q1RML9
    Conserved Domains (1) summary
    pfam03403
    Location:52 → 417
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

  2. XM_005223379.5 → XP_005223436.1  platelet-activating factor acetylhydrolase isoform X2

    See identical proteins and their annotated locations for XP_005223436.1

    UniProtKB/Swiss-Prot
    Q28017
    Conserved Domains (1) summary
    pfam03403
    Location:7 → 372
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

  3. XM_005223378.5 → XP_005223435.1  platelet-activating factor acetylhydrolase isoform X2

    See identical proteins and their annotated locations for XP_005223435.1

    UniProtKB/Swiss-Prot
    Q28017
    Conserved Domains (1) summary
    pfam03403
    Location:7 → 372
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

  4. XM_005223377.4 → XP_005223434.1  platelet-activating factor acetylhydrolase isoform X1

    See identical proteins and their annotated locations for XP_005223434.1

    UniProtKB/Swiss-Prot
    Q28017
    UniProtKB/TrEMBL
    Q1RML9
    Conserved Domains (1) summary
    pfam03403
    Location:52 → 417
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II

  5. XM_010818166.3 → XP_010816468.1  platelet-activating factor acetylhydrolase isoform X1

    See identical proteins and their annotated locations for XP_010816468.1

    UniProtKB/Swiss-Prot
    Q28017
    UniProtKB/TrEMBL
    Q1RML9
    Conserved Domains (1) summary
    pfam03403
    Location:52 → 417
    PAF-AH_p_II; Platelet-activating factor acetylhydrolase, isoform II
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28017.1 GenPept UniProtKB/Swiss-Prot:Q28017

Gene LinkOut

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