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RASSF2 Ras association domain family member 2 [ Bos taurus (domestic cattle) ]

Gene ID: 282337, updated on 30-Jan-2025

Summary

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Official Symbol
RASSF2provided by VGNC
Official Full Name
Ras association domain family member 2provided by VGNC
Primary source
VGNC:VGNC:33758
See related
BGD:BT11977; EnsemblRapid:ENSBTAG00070015155
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See RASSF2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (47131128..47190117, complement)

Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene prion protein Neighboring gene prion like protein doppel Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 23 member 2 Neighboring gene transfer RNA tryptophan (anticodon CCA)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Isolation and molecular characterization of rasfadin, a novel gene in the vicinity of the bovine prion gene. Comincini S, et al. Mamm Genome, 2001 Feb. PMID 11210185
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras association domain-containing protein 2
Names
Ras association (RalGDS/AF-6) domain family 2
Ras association domain family 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001435126.1 → NP_001422055.1  ras association domain-containing protein 2

    Status: VALIDATED

    Source sequence(s)
    NKLS02000013
    Related
    ENSBTAP00070020259.1, ENSBTAT00070034224.1

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    47131128..47190117 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005214436.4 → XP_005214493.1  ras association domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005214493.1

    UniProtKB/TrEMBL
    E1BCV3
    Conserved Domains (2) summary
    cd01784
    Location:177 → 263
    rasfadin_RA; Ubiquitin-like domain of Rasfadin
    pfam16517
    Location:277 → 316
    Nore1-SARAH; Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain

  2. XM_015474079.3 → XP_015329565.1  ras association domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    E1BCV3
    Conserved Domains (2) summary
    cd01784
    Location:177 → 263
    rasfadin_RA; Ubiquitin-like domain of Rasfadin
    pfam16517
    Location:277 → 316
    Nore1-SARAH; Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_174593.2: Suppressed sequence

    Description
    NM_174593.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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