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ATP2B1 ATPase plasma membrane Ca2+ transporting 1 [ Bos taurus (domestic cattle) ]

Gene ID: 282641, updated on 30-Jan-2025

Summary

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Official Symbol
ATP2B1provided by VGNC
Official Full Name
ATPase plasma membrane Ca2+ transporting 1provided by VGNC
Primary source
VGNC:VGNC:26293
See related
BGD:BT12477; EnsemblRapid:ENSBTAG00070020780
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
PMCA
Orthologs
human mouse all
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Genomic context

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See ATP2B1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (19474153..19607430, complement)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112446834 Neighboring gene small ribosomal subunit protein eS26-like Neighboring gene uncharacterized LOC112446883 Neighboring gene uncharacterized LOC132345243

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. Localization and regulation of plasma membrane Ca(2+)-ATPase in bovine spermatozoa. Triphan J, et al. Eur J Cell Biol, 2007 May. PMID 17397965
  2. Salmonella serotype Typhimurium infection of bovine Peyer's patches down-regulates plasma membrane calcium-transporting ATPase expression. Santos RL, et al. J Infect Dis, 2002 Aug 1. PMID 12134233
  3. Matrix metalloprotease 2-mediated activation of Ca(2+)-ATPase by superoxide radical (O2*-) in plasma membrane of bovine pulmonary vascular smooth muscle. Mandai M, et al. Indian J Biochem Biophys, 2002 Dec. PMID 22905396
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables P-type calcium transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables PDZ domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plasma membrane calcium-transporting ATPase 1
Names
ATPase, Ca++ transporting, plasma membrane 1
plasma membrane calcium ATPase 1
NP_777121.1
XP_005206101.1
XP_010803067.1
XP_024847147.1
XP_024847150.1
XP_059742106.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174696.2 → NP_777121.1  plasma membrane calcium-transporting ATPase 1

    Status: PROVISIONAL

    Source sequence(s)
    AF332982
    UniProtKB/TrEMBL
    A0A3Q1MDH1, Q95ML6
    Related
    ENSBTAP00070028128.1, ENSBTAT00070046961.1
    Conserved Domains (7) summary
    TIGR01517
    Location:15 → 1064
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:195 → 464
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:880 → 1058
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 121
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1103 → 1150
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:687 → 806
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:525 → 611
    Cation_ATPase; Cation transport ATPase (P-type)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19474153..19607430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024991379.2 → XP_024847147.1  plasma membrane calcium-transporting ATPase 1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1MDH1, F1N7J2
    Conserved Domains (2) summary
    TIGR01517
    Location:15 → 1064
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12424
    Location:1103 → 1149
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal

  2. XM_010804765.4 → XP_010803067.1  plasma membrane calcium-transporting ATPase 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MDH1, A0A3Q1ND98
    Conserved Domains (2) summary
    TIGR01517
    Location:15 → 1064
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12424
    Location:1103 → 1178
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal

  3. XM_024991382.2 → XP_024847150.1  plasma membrane calcium-transporting ATPase 1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1MDH1
    Conserved Domains (2) summary
    TIGR01517
    Location:15 → 1064
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12424
    Location:1103 → 1142
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal

  4. XM_059886123.1 → XP_059742106.1  plasma membrane calcium-transporting ATPase 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MDH1, A0A3Q1ND98

  5. XM_005206044.4 → XP_005206101.1  plasma membrane calcium-transporting ATPase 1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MDH1, A0A3Q1ND98
    Related
    ENSBTAP00070028117.1, ENSBTAT00070046941.1
    Conserved Domains (2) summary
    TIGR01517
    Location:15 → 1064
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam12424
    Location:1103 → 1178
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
Nucleotide Protein Strain
Heading Accession and Version

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