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PYCARD PYD and CARD domain containing [ Bos taurus (domestic cattle) ]

Gene ID: 282846, updated on 27-Dec-2024

Summary

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Gene symbol
PYCARD
Gene description
PYD and CARD domain containing
See related
BGD:BT14986; Ensembl:ENSBTAG00000020535
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
ASC
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Genomic context

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See PYCARD in Genome Data Viewer
Location:
chromosome: 25
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (27285066..27286399, complement)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107131831 Neighboring gene serine protease 36 Neighboring gene FUS RNA binding protein Neighboring gene tripartite motif containing 72 Neighboring gene integrin subunit alpha M

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. Masumoto J, et al. J Biol Chem, 1999 Nov 26. PMID 10567338
  2. Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos. Masumoto J, et al. Exp Cell Res, 2001 Jan 15. PMID 11139337
  3. Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development. Masumoto J, et al. J Biol Chem, 2003 Feb 7. PMID 12464617
  4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptosis-associated speck-like protein containing a CARD
Names
PYD and CARD domain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174730.2 → NP_777155.1  apoptosis-associated speck-like protein containing a CARD

    See identical proteins and their annotated locations for NP_777155.1

    Status: PROVISIONAL

    Source sequence(s)
    BC102385
    UniProtKB/Swiss-Prot
    Q8HXK9
    UniProtKB/TrEMBL
    A0AAA9TU74
    Related
    ENSBTAP00000027359.2, ENSBTAT00000027359.3
    Conserved Domains (2) summary
    cd08321
    Location:5 → 87
    Pyrin_ASC-like; Pyrin Death Domain found in ASC
    cd08330
    Location:113 → 193
    CARD_ASC_NALP1; Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    27285066..27286399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8HXK9.1 GenPept UniProtKB/Swiss-Prot:Q8HXK9

Gene LinkOut

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Molecular Biology Databases
Research Materials