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LINC00523 long intergenic non-protein coding RNA 523 [ Homo sapiens (human) ]

Gene ID: 283601, updated on 10-Dec-2024

Summary

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Official Symbol
LINC00523provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 523provided by HGNC
Primary source
HGNC:HGNC:20117
See related
Ensembl:ENSG00000196273 AllianceGenome:HGNC:20117
Gene type
ncRNA
RefSeq status
PREDICTED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf70
Expression
Low expression observed in reference dataset See more
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Genomic context

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See LINC00523 in Genome Data Viewer
Location:
14q32.2
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (100657268..100672744)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (94891104..94906582)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (101123605..101139081)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903382 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9041 Neighboring gene brain enriched guanylate kinase associated Neighboring gene uncharacterized LOC124903384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101021873-101022628 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101022629-101023385 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101069891-101070390 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:101081529-101081726 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101102218-101103218 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101105157-101105658 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101105659-101106158 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6092 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101111512-101112012 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr14:101126859-101128058 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101132935-101133436 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101139493-101140240 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101145673-101146266 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101146861-101147454 Neighboring gene uncharacterized LOC105370668 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:101155275-101156090 Neighboring gene uncharacterized LOC124903385

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Downregulation of long non-coding RNAs LINC00523 and LINC00994 in type 2 diabetes in an Iranian cohort. Mansoori Z, et al. Mol Biol Rep, 2018 Oct. PMID 30043104
  2. Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development. Wang P, et al. J Clin Invest, 2019 Jul 25. PMID 31343991, Free PMC Article
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024096.1 RNA Sequence

    Status: PREDICTED

    Source sequence(s)
    BX161445
    Related
    ENST00000360899.3

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    100657268..100672744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    94891104..94906582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001007560.1: Suppressed sequence

    Description
    NM_001007560.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86TU6.1 GenPept UniProtKB/Swiss-Prot:Q86TU6

Gene LinkOut

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Chemical Information
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