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ldrD small toxic polypeptide LdrD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 2847730, updated on 3-Dec-2024

Summary

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Official Symbol
ldrD
Official Full Name
small toxic polypeptide LdrD
Primary source
ECOCYC:G0-9041
Locus tag
b4453
See related
ASAP:ABE-0047284
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3524
Summary
ldrD is one of a set of four Long Direct Repeats (LDRs), and has been shown to code for the toxin portion of a toxin-antitoxin pair. [More information is available at EcoCyc: G0-9041].
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Genomic context

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Sequence:
NC_000913.3 (3699980..3700087, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene c-di-GMP-binding protein BcsE Neighboring gene putative cellulose biosynthesis protein BcsF Neighboring gene cellulose phosphoethanolamine transferase Neighboring gene ncRNA Neighboring gene putative transporter YhjV

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Distribution of repetitive sequences on the leading and lagging strands of the Escherichia coli genome: comparative study of Long Direct Repeat (LDR) sequences. Kawano M, et al. DNA Res, 2002 Feb 28. PMID 11939563
  2. Hydrophobic peptides: novel regulators within bacterial membrane. Alix E, et al. Mol Microbiol, 2009 Apr. PMID 19210615
  3. Molecular characterization of long direct repeat (LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cis-encoded small antisense RNA in Escherichia coli. Kawano M, et al. Mol Microbiol, 2002 Jul. PMID 12123448
  4. Repression of small toxic protein synthesis by the Sib and OhsC small RNAs. Fozo EM, et al. Mol Microbiol, 2008 Dec. PMID 18710431, Free PMC Article
  5. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
small toxic polypeptide LdrD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3699980..3700087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026227.1 small toxic polypeptide LdrD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026227.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    pfam13940
    Location:1 → 35
    Ldr_toxin; Toxin Ldr, type I toxin-antitoxin system
Nucleotide Protein
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