U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NDST2 N-deacetylase and N-sulfotransferase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 286838, updated on 29-Jan-2025

Summary

Go to the top of the page Help
Gene symbol
NDST2
Gene description
N-deacetylase and N-sulfotransferase 2
See related
BGD:BT20546; Ensembl:ENSBTAG00000012664
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See NDST2 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (29696608..29704955, complement)

Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1 Neighboring gene zinc finger SWIM-type containing 8 Neighboring gene calcium/calmodulin dependent protein kinase II gamma Neighboring gene plasminogen activator, urokinase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The putative heparin-specific N-acetylglucosaminyl N-Deacetylase/N-sulfotransferase also occurs in non-heparin-producing cells. Toma L, et al. J Biol Chem, 1998 Aug 28. PMID 9712870
  2. Characterization of gene expression profiles in early bovine pregnancy using a custom cDNA microarray. Ishiwata H, et al. Mol Reprod Dev, 2003 May. PMID 12658628
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC154982

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables [heparan sulfate]-glucosamine N-sulfotransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2
Names
CCL44
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
N-deacetylase/N-sulfotransferase 2
NDST-2
glucosaminyl N-deacetylase/N-sulfotransferase 2
NP_777202.2
XP_005226388.1
XP_010818836.1
XP_024842343.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174777.3 → NP_777202.2  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

    See identical proteins and their annotated locations for NP_777202.2

    Status: PROVISIONAL

    Source sequence(s)
    BC134688
    UniProtKB/Swiss-Prot
    O97583, Q862Q7, Q862Y7
    UniProtKB/TrEMBL
    A8E4L2
    Related
    ENSBTAP00070037448.1, ENSBTAT00070062593.1
    Conserved Domains (2) summary
    pfam00685
    Location:603 → 852
    Sulfotransfer_1; Sulfotransferase domain
    pfam12062
    Location:25 → 514
    HSNSD; heparan sulfate-N-deacetylase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    29696608..29704955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005226331.5 → XP_005226388.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X1

    See identical proteins and their annotated locations for XP_005226388.1

    UniProtKB/Swiss-Prot
    O97583, Q862Q7, Q862Y7
    UniProtKB/TrEMBL
    A8E4L2
    Conserved Domains (2) summary
    pfam00685
    Location:603 → 852
    Sulfotransfer_1; Sulfotransferase domain
    pfam12062
    Location:25 → 514
    HSNSD; heparan sulfate-N-deacetylase

  2. XM_024986575.2 → XP_024842343.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X3

    UniProtKB/Swiss-Prot
    O97583, Q862Q7, Q862Y7
    UniProtKB/TrEMBL
    A0A3Q1LTF8
    Related
    ENSBTAP00070037468.1, ENSBTAT00070062614.1
    Conserved Domains (2) summary
    pfam00685
    Location:541 → 790
    Sulfotransfer_1; Sulfotransferase domain
    pfam12062
    Location:25 → 452
    HSNSD; heparan sulfate-N-deacetylase

  3. XM_010820534.4 → XP_010818836.1  bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform X2

    UniProtKB/Swiss-Prot
    O97583, Q862Q7, Q862Y7
    Conserved Domains (2) summary
    pfam00685
    Location:603 → 835
    Sulfotransfer_1; Sulfotransferase domain
    pfam12062
    Location:25 → 514
    HSNSD; heparan sulfate-N-deacetylase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O97583.1 GenPept UniProtKB/Swiss-Prot:O97583

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.