Tmsb15b2 thymosin beta 15B2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tmsb15b2provided by RGD
Official Full Name: thymosin beta 15B2provided by RGD
Primary source: RGD:708373
See related: EnsemblRapid:ENSRNOG00000037661 AllianceGenome:RGD:708373
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Tmsbl1
Summary: Predicted to enable actin monomer binding activity. Predicted to be involved in positive regulation of cell migration and sequestering of actin monomers. Predicted to act upstream of or within negative regulation of actin filament polymerization and negative regulation of stress fiber assembly. Predicted to be located in stress fiber. Predicted to be part of filamentous actin. Predicted to be active in cytoplasm. Orthologous to several human genes including TMSB15A (thymosin beta 15A). [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in Testes (RPKM 591.0), Brain (RPKM 149.4) and 6 other tissues See more
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Genomic context

Location:: Xq32

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (105090980..105093094, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (100298705..100300820, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (107612518..107614632, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables actin monomer binding	IBA Inferred from Biological aspect of Ancestor more info
enables actin monomer binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in actin filament organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of actin filament polymerization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within negative regulation of stress fiber assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cell migration	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in sequestering of actin monomers	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sequestering of actin monomers	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of filamentous actin	ISO Inferred from Sequence Orthology more info
located_in stress fiber	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: thymosin beta-15B

Names: thymosin beta-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.