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Vom2r75 vomeronasal 2 receptor, 75 [ Rattus norvegicus (Norway rat) ]

Gene ID: 286986, updated on 4-Jan-2025

Summary

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Official Symbol
Vom2r75provided by RGD
Official Full Name
vomeronasal 2 receptor, 75provided by RGD
Primary source
RGD:708414
See related
EnsemblRapid:ENSRNOG00000022955 AllianceGenome:RGD:708414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
Expression
Restricted expression toward (RPKM 17.3) See more
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Genomic context

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See Vom2r75 in Genome Data Viewer
Location:
18p13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (84553..114196, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (70194..99837, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (11936..38488, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene BRCA1/BRCA2-containing complex, subunit 3, pseudogene 7 Neighboring gene C-X9-C motif containing 4 Neighboring gene FUN14 domain containing 2 Neighboring gene mature T-cell proliferation 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution. Herrada G, et al. Cell, 1997 Aug 22. PMID 9288755
  2. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal 2 receptor, 75
Names
pheromone receptor (Go-VN13B)-like
putative pheromone receptor (Go-VN13B)
putative pheromone receptor Go-VN13C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419486.1 → NP_001406415.1  vomeronasal 2 receptor, 75 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    A0A8I6AS76, G3V911
    Related
    ENSRNOP00000032871.3, ENSRNOT00000036914.5

  2. NM_173320.2 → NP_775442.2  vomeronasal 2 receptor, 75 isoform 2 precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000018
    UniProtKB/TrEMBL
    A6KNC0, O35271
    Conserved Domains (3) summary
    cd15283
    Location:551 → 786
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:41 → 503
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:512 → 552
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    84553..114196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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