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Zswim7 zinc finger, SWIM-type containing 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287388, updated on 4-Jan-2025

Summary

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Official Symbol
Zswim7provided by RGD
Official Full Name
zinc finger, SWIM-type containing 7provided by RGD
Primary source
RGD:1310324
See related
AllianceGenome:RGD:1310324
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310324
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein stabilization. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure 71. Orthologous to human ZSWIM7 (zinc finger SWIM-type containing 7). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 73.7), Testes (RPKM 59.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zswim7 in Genome Data Viewer
Location:
10q23
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (47456843..47469084, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (46953311..46969800, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (48587117..48599208, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 Neighboring gene selenoprotein W, pseudogene 1 Neighboring gene adenosine A2B receptor Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene nuclear receptor co-repressor 1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class L Neighboring gene transmembrane p24 trafficking protein 4, pseudogene 1 Neighboring gene centromere protein V

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair. Liu T, et al. J Biol Chem, 2011 Dec 2. PMID 21965664, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in double-strand break repair via homologous recombination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of Shu complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Shu complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger SWIM domain-containing protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163492.1 → NP_001156964.1  zinc finger SWIM domain-containing protein 7

    See identical proteins and their annotated locations for NP_001156964.1

    Status: VALIDATED

    Source sequence(s)
    BF522197, BQ209551
    UniProtKB/TrEMBL
    A6HF95

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    47456843..47469084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268625.1 → XP_063124695.1  zinc finger SWIM domain-containing protein 7 isoform X3

  2. XM_039085421.2 → XP_038941349.1  zinc finger SWIM domain-containing protein 7 isoform X2

  3. XM_039085419.2 → XP_038941347.1  zinc finger SWIM domain-containing protein 7 isoform X1

RNA

  1. XR_010055149.1 RNA Sequence

  2. XR_010055148.1 RNA Sequence

  3. XR_010055147.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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