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Or1e1 olfactory receptor family 1 subfamily E member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 287480, updated on 27-Nov-2024

Summary

Official Symbol
Or1e1provided by RGD
Official Full Name
olfactory receptor family 1 subfamily E member 1provided by RGD
Primary source
RGD:1333989
See related
EnsemblRapid:ENSRNOG00000087212 AllianceGenome:RGD:1333989
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Olr1466
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Expression
Biased expression in Kidney (RPKM 7.5) and Testes (RPKM 1.8) See more
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Genomic context

See Or1e1 in Genome Data Viewer
Location:
10q24
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (58470917..58476388)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (57975519..57976463)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (59919064..59924512)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel, subfamily V, member 3 Neighboring gene aspartoacylase Neighboring gene spermatogenesis associated 22 Neighboring gene uncharacterized LOC103693362 Neighboring gene olfactory receptor family 1 subfamily E member 1C Neighboring gene lymphocyte antigen 6 family member E, pseudogene 1 Neighboring gene olfactory receptor family 1 subfamily E member 18

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor Olr1466
Names
olfactory receptor 1466
olfactory receptor gene Olr1466

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001000024.1NP_001000024.1  olfactory receptor Olr1466

    See identical proteins and their annotated locations for NP_001000024.1

    Status: REVIEWED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I6A849, A6HGK0
    Related
    ENSRNOP00000107423.1, ENSRNOT00000148964.1
    Conserved Domains (2) summary
    pfam00001
    Location:41290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31308
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    58470917..58476388
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063268673.1XP_063124743.1  olfactory receptor Olr1466 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A849